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Sounds Like: PAL.uh.done
Classification: Opioid
Controlled Substance Act Schedule: Schedule II
Other names for Palladone
Palladone can have adverse effects when used for an elongated duration, but it also has many of the same effects if it’s just taken at high dosage, regardless of the regularity of use. The same is the case if the medication is taken by a patient with preexisting kidney dysfunction. Those adverse effects include neuroexcitatory presentations like agitation, cognitive dysfunction, myoclonus and tremor. It’s a lesser neurotoxicity than that of some other opioids, however, like those of the pethidine synthetics.
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Hydromorphone, or Palladone, is primarily prescribed as treatment for moderate to severe pain. Its effects usually start within half an hour of administering the medication. From there, they last up to five hours depending on how much tolerance the body may or may not have built up for Palladone. Physicians only ever prescribe short-term use for Hydromorphone because of its propensity for developing dependency. However, oncologists usually make exceptions for their patients and prescribe long-term use for those whose pain is related to cancer.
Palladone is administered as a pill most often. It can, however, be injected into a vein, muscle or just under the skin.
Allowing shorter and shorter intervals of time to elapse between uses
The need to take doses either before or after every meal (or both)
Prioritizing use of the drug over spending time with family or friends
Overdosing more than once
Palladone has been used in the state of Ohio via intramuscular injection during executions of the death penalty. It’s administered in conjunction with midazolam as a backup plan for when executioners can’t find a suitable vein for intravenous injection.
A build-up in levels of hydromorphone-3-glucoronide can lead to excitatory neurotoxic effects that include restlessness, myoclonus and hyperalgesia.
Hydromorphone Hcl typically costs about $80.60 for 120 four-mg. tablets.