(888) 448-0302 Talk to a recovery specialist 24/7

Choosing recovery close to home means your support system is just a few miles away.

  • 100% Confidential
  • Available 24/7
  • No Pressure to Commit
  • Multiple Financial Options Available
Call (888) 448-0302

We're Here To Help 24/7

What is Etizolam?

by Will Long

November 24, 2021
What is etizolam?

Updated: August 2, 2023, at 9:31 a.m.

Etizolam (sometimes known as “street valium) is a thienodiazepine, a class of drugs closely related to benzodiazepines. The drug is 10 times as potent as diazepam, commonly known by its trade name Valium. Regularly prescribed in several countries, including Japan, etizolam can be found at doses ranging from 0.25mg to 1mg in tablet form for anxiety and sleep disorders. On the black market side, it’s sold as a tablet, in blotter paper, dissolved in propylene glycol, or as a powder and is usually billed in the U.S. as a “research chemical, ” primarily used in tablet form.


It’s an anxiolytic to some degree, much more so than benzodiazepines; etizolam is primarily a kind of CNS depressant, like alcohol is. It acts as a full agonist at the benzodiazepine/GABAa receptor to produce its range of therapeutic and adverse effects. Etizolam has the ability to turn the user into a disoriented amnesiac at a high enough dose.

Like naloxone does for opioid overdoses, flumazenil, a GABA antagonist, can stop effects of etizolam and reverse benzodiazepine overdoses. On the opposite end of the spectrum, GABA agonists can fatally interact with etizolam. Withdrawal to etizolam can take the form of benzodiazepine withdrawal effects due to the similarity of the drugs. Tapering is necessary due to the risk of fatal effects that a cold turkey stoppage could cause.

Recreational use

First appearing recreationally in the US around 2011, etizolam has gained popularity as a recreational drug of choice. There has been rising concern since 2014 in regional US pockets, but due to the uptick in national cases of etizolam use, it has since become an issue of national concern.

Etizolam appeals to “research chemical” users because of its federally unscheduled status; it’s legal for research purposes in all states. The drug is scheduled on the state level in the following states:

  • Alabama
  • Arkansas
  • Florida
  • Georgia
  • Indiana
  • Louisiana
  • Mississippi
  • Ohio
  • South Carolina
  • Virginia

“Major adverse effects include drowsiness, sedation, muscle weakness and incoordination, fainting, headache, confusion, depression, slurred speech, visual disturbances, and changes in libido and tremor.” – DEA Diversion Fact Sheet

It’s very likely that etizolam will attain scheduled status in the US in the near future. As a dangerous drug that’s relatively little used for legit medical prescriptions in the West, etizolam is one to watch out for.

Learn more

Partner with Landmark Recovery to help unlock your potential and beat addiction. Call us today at 888-448-0302.

recovery specialist available 24 hours a day at landmark recovery

Choose Recovery Over Addiction

We're here 24/7 to help you get the care you need to live life on your terms, without drugs or alcohol. Talk to our recovery specialists today and learn about our integrated treatment programs.

About the Author

Will Long

Will Long

A graduate of Middle Tennessee State University, Long has been a writer for Landmark Recovery since 2021. He specializes in research and writing about substance abuse from a scientific and social perspective. Unearthing information from underexplored, far-flung corners of the Internet, Long’s passion is finding emerging trends in substance use and treatment that the public should know about.