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What Is AN 627?

by Landmark Recovery

February 12, 2025
addiction treatment specialist speaking with young woman in an office setting explaining what is AN 627 and how presciption pills can be addictive.

When researching pain medications, you may come across the AN 627 pill. This prescription medication is a widely used analgesic that combines two key ingredients to help manage moderate pain. If you or a loved one is using this medication, understanding its effects, risks, and proper use is essential.

For those struggling with substance use, Landmark Recovery provides medical detox services and comprehensive treatment programs to support long-term healing.

What Is AN 627?

AN 627 is an imprint found on a specific prescription pain medication containing tramadol hydrochloride 50 mg. Tramadol is an opioid-like pain reliever that works by altering how the brain perceives pain signals. It is commonly prescribed for moderate to moderately severe pain but must be used cautiously due to its potential for dependence and side effects.

While tramadol is considered less potent than traditional opioids like oxycodone or morphine, it still carries risks, particularly when misused or taken without medical supervision.

AN 627 Pill: Onset and Duration

A common concern for individuals prescribed AN 627 is how quickly the medication takes effect and how long it lasts.

  • Onset – The AN 627 pill typically begins to relieve pain within 30 to 60 minutes after ingestion.
  • Peak effects – The strongest effects occur between two to three hours after taking the pill.
  • Duration—Pain relief generally lasts four to six hours, making it a short-acting pain reliever that may require multiple doses daily, as directed by a physician.

Because the medication is fast-acting, it is often used for acute pain rather than chronic pain conditions that require long-term management.

AN 627 Detection Time

For individuals undergoing drug testing, understanding the AN 627 detection time is important. Different tests can detect tramadol in the system for varying lengths of time:

  • Urine test – Detectable for one to four days after the last dose
  • Blood test – Detectable for up to 24 hours
  • Saliva test – Detectable for one to two days
  • Hair test – Can show traces of tramadol for up to 90 days

Factors like metabolism, dosage, and frequency of use can influence how long AN 627 remains in the body.

Precautions and Safety Guidelines

Like any prescription medication, the AN 627 pill should be used as directed by a healthcare provider. Here are some critical precautions to keep in mind:

  • Avoid alcohol and other depressants – Combining AN 627 with alcohol, benzodiazepines, or other sedatives increases the risk of dangerous side effects, including respiratory depression.
  • Risk of dependence – Long-term use or taking higher doses than prescribed can lead to dependence, withdrawal symptoms, or overdose.
  • Medical conditions – People with a history of seizures, liver or kidney disease, or respiratory issues should consult their doctor before using AN 627.
  • Pregnancy and breastfeeding – Tramadol use during pregnancy can cause withdrawal symptoms in newborns, so it should only be used if absolutely necessary.

Proper Storage and Disposal of AN 627

To ensure the safety of others, proper storage and disposal of AN 627 is essential.

Storage Guidelines

  • Keep the medication in its original container, away from moisture and heat.
  • Store it out of reach of children and pets.
  • Avoid keeping unused medication in common household areas where others might access it.

Disposal Instructions

  • Do not flush AN 627 down the toilet unless instructed by a pharmacist or local regulations.
  • Use a drug take-back program at a pharmacy or community disposal site.
  • If a take-back program is unavailable, mix the medication with an unappealing substance, such as coffee grounds or cat litter, seal it in a bag, and throw it in the trash.

AN 627 Dangers and Risks

Although AN 627 is a commonly prescribed medication, it carries certain risks, particularly when misused.

Common Side Effects

  • Dizziness
  • Nausea
  • Constipation
  • Drowsiness
  • Dry mouth

Serious Risks

  • Respiratory depression – High doses or combining AN 627 with other central nervous system depressants can slow breathing to dangerous levels.
  • Seizures – Higher doses or interactions with other medications may trigger seizures, particularly in individuals with epilepsy.
  • Serotonin syndrome – When combined with antidepressants or other serotonergic medications, AN 627 can cause a life-threatening reaction that includes confusion, rapid heart rate, and high fever.
  • Overdose – Taking too much AN 627 can result in unconsciousness, slowed breathing, and potential fatality. Seek emergency medical attention if an overdose is suspected.

Seeking Help for Tramadol Dependence

If you or someone you care about is struggling with tramadol dependence, help is available. Landmark Recovery offers a full spectrum of care, from medical detox to residential treatment and outpatient programs, to support individuals through the recovery process.

With locations in Arkansas, Colorado, Indiana, Kentucky, and Ohio, as well as new centers in Colorado Springs and Cleveland, Landmark Recovery provides evidence-based care tailored to your needs. Whether you require detox support, therapy, or long-term recovery planning, our compassionate team is here to help.

Contact Landmark Recovery Today

Don’t wait to take the first step toward recovery. If you or a loved one needs support for substance use, contact Landmark Recovery to learn more about our detox, residential, and outpatient programs. Our team is dedicated to guiding you toward lasting healing.

Call us today at (888) 448-0302 or complete our online form to start your journey to recovery.

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About the Author

Landmark Recovery

Landmark Recovery

Landmark Recovery was founded with a determination to make addiction treatment accessible for all. Through our integrated treatment programs, we've helped thousands of people choose recovery over addiction and get back to life on their own terms. We're on a mission to save one million lives over the next century. We encourage all those struggling with substance use to seek professional help.